You may have heard of the fantastic-sounding "dark side of the genome." This poorly studied fraction of DNA, known as ...

Researchers have shown that 5mC is associated with genes turned "off" while 5hmC, mediated by TET proteins, is associated with gene expression turned "on." This "on/off" epigenetic system gives ...

This allows researchers to sequence all four DNA bases and distinguish between 5mC and 5hmC. Using the data analysis package, researchers obtain a single multiomic dataset from which they can assess ...

The answers to such questions lie in the study of gene expression. Thus, this collection or articles begins by showing how a quiet, well-guarded string of DNA is expressed to make RNA, and how the ...