Caption (A) ABC transporters: The normal functioning of ABCG8/ABCG5, ABCB4, and ABCB11 enables the transport of cholesterol, bile acids, and lipids into bile (left). Mutations in any of these ...

These bile-acid-controlled signalling pathways have become the source of promising novel drug targets to treat common metabolic and hepatic diseases ... bile-acid transporters exert crucial ...