Immune cells in the bone marrow microenvironment of AML patients are key in distinguishing a response to immunotherapy.

Discover how groundbreaking research on unique immune cells and advanced AI tools offers renewed hope for improving cancer ...

Galinpepimut-S therapy showed specific T-Cell immune responses for patients with acute myeloid leukemia in remission ...

has now shown that TP53-mutant AML cells are also significantly more resistant to a new type of immunotherapy—CAR T-cell therapy—than AML cells without the mutated gene. The paper is published ...

Columbia Engineering and Irving Institute researchers unveil a significant finding in cancer immunotherapy, uncovering unique T cells pivotal in treating relapsed acute myeloid leukemia. Their DIISCO ...

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In this regard, natural killer (NK) cell-based immunotherapy has attracted clinical interest due to its critical role in immunosurveillance and their capabilities to target AML blasts. NK cells ...

In cancer immunotherapy, T cells are often the stars of the show ... cells when he realized that they offered a unique opportunity to treat blood cancers like acute myeloid leukemia (AML). Previous ...

Oncolytic viruses are therapeutic agents used for in situ immunization in cancer immunotherapy. Unfortunately, its efficacy is particularly limited in solid tumors expressing stimulator of interferon ...

In addition, depletion of Treg, has shown to dramatically improve efficacy of adoptive cytotoxic T-cell immunotherapy in a murine AML model. Zhou et al. demonstrated that a brief course of ...

why do some patients benefit from immunotherapy while others do not? The current treatment for relapsed AML, donor lymphocyte infusion (DLI) -- a therapy involving donor immune cells -- has a 5 ...

A research team from Columbia Engineering and the Irving Institute for Cancer Dynamics achieved a significant finding in cancer immunotherapy.The team discovered a unique population of immune cells ...