Angiotensin contributes to the production of aldosterone, which normally acts to retain sodium and water. ACE inhibitors are used to treat hypertension, systolic congestive heart failure and as ...

Aldosterone was originally thought to be blocked by ACE inhibitors. However, it is now known that usual doses of ACE inhibitors do not completely suppress aldosterone production. Furthermore ...

According to current medical guidelines, several types of medications are recommended for treating high blood pressure. These ...

Purpose: The clinical benefits, adverse effects, pharmacokinetics, and recommendations for the appropriate use of the aldosterone antagonists spironolactone and eplerenone in patients with heart ...