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The outer tissue of the adrenal glands, known as the adrenal cortex, has three layers that secrete three different hormones: ...

Purpose: The clinical benefits, adverse effects, pharmacokinetics, and recommendations for the appropriate use of the aldosterone antagonists spironolactone and eplerenone in patients with heart ...

In the presence of neurohormonal activation, angiotensin II causes aldosterone production in the adrenal cortex, which acts on the cortical collecting tubules to conserve sodium. Aldosterone may ...

The adrenal glands are small triangular glands located at the top of the kidneys. Addison's disease occurs when the adrenal glands do not produce enough hormones due to either the adrenal cortex not ...

Adrenaline, 'the fight or flight' stress hormone, is produced in the medulla core. The cortex is responsible for essential steroid hormones cortisol and aldosterone which are produced in different ...

Aldosterone antagonists (spironolactone, eplerenone) also known as “potassium sparing diuretics” block the action of aldosterone inhibiting the reuptake of sodium and water. Normally, when ...