Sodium reabsorption is mainly controlled by aldosterone, a steroid hormone synthesized in the zona glomerulosa of the adrenal gland, secondary to renin stimulation via angiotensin II and to ...

Due to their location, APAs are a major cause of primary aldosteronism, a condition in which excessive production of the hormone aldosterone leads to high blood pressure. Primary aldosteronism is ...

Researchers have discovered that a common form of high blood pressure is caused by tiny, non-cancerous growths in the adrenal ...

Abbreviations: ACTH = adrenocorticotropic hormone; AME = apparent mineralocorticoid ... b Due to production of non-aldosterone mineralocorticoids. c Acquired forms due to DOC-producing tumors.

Aldosterone antagonists (spironolactone, eplerenone) also known as “potassium sparing diuretics” block the action of aldosterone inhibiting the reuptake of sodium and water. Normally, when ...

Purpose: The clinical benefits, adverse effects, pharmacokinetics, and recommendations for the appropriate use of the aldosterone antagonists spironolactone and eplerenone in patients with heart ...

Due to their location, APAs are a major cause of primary aldosteronism, a condition in which excessive production of the hormone aldosterone leads to high blood pressure. Primary aldosteronism is ...