The discovery of a potential protein ... cell death leads to a gradual loss of muscle control, and usually results in death by respiratory failure within a decade of diagnosis. Although the causes ...

Neuronal cells clogged with a mutant protein associated with amyotrophic lateral sclerosis (ALS) die within hours after the clumps first form, researchers report in this month's Journal of Cell ...

Protein complexes within each cell further connect the transmembrane adhesive proteins to the cytoskeleton. In particular, adaptor complexes bind adherens junctions to cytoskeletal actin ...

1 Some ALS patients also experience cognitive decline and behavioral changes. Gag-pol contains a retroviral protease domain, which it uses to cut itself and the gag form into pieces. Using a ...