To put the whole 8 MB thing in context, one GPU from the HL2 period was the ATI (now AMD) Radeon 9700 which launched in 2002 and had 128 MB of VRAM. And as the YouTuber points out, a lot of cards back ...

undersampling can and does occur when peptide mixtures entering the mass spectrometer are complex. Undersampling means that repeated analyses may not yield exactly the same protein identifications ...