The drug, named mandimycin, is a member of a known family of bacterial products with antifungal properties, the polyene ...

Mandimycin is structurally similar to the last-line-of-defense antifungal amphotericin B, another glycosylated polyene macrolide. But instead of binding to ergosterol in the fungal cell membrane as ...

When most people think of dangerous infections, they picture bacteria or viruses. But for infectious disease specialists like ...

F2G, an antifungal-focused biopharma company ... of orotomides is currently in clinical-stage development with other compounds such as fosmanogepix and new formulations of polyenes are in varying ...

NovaBiotics’ platform technologies leverage defense strategies of the innate immune system and provide first-in-class antibacterial and antifungal ... novel classes of compounds that target ...