Though much has been said on this topic already 1,2,3,4, the concept of a 'chemical probe' that can be used to investigate biology has become embedded in the scientific lexicon without an accepted ...
The following is a summary of “Diagnostic-avoiding Chlamydia trachomatis variants detected in cervical and endometrial ...
In a recent study, PAC-MANN identified pancreatic ductal adenocarcinoma samples with 98% specificity and 73% sensitivity ...
Starting with an existing assay, investigators performed probe screening in serum from patients with PDAC or who were cancer free. The work identified a single peptide probe that could distinguish ...
In order to definitively demonstrate that it was an HNF-4 protein binding to their promoter, the investigators next performed a supershift assay. By mixing the labeled probe and nuclear extract ...
They identified a matrix metalloproteinase-2 (MMP2)–sensitive probe that could distinguish patients with and without PDAC and used it to develop the PAC-MANN-1 assay for detecting PDAC by ...
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Nanosensor Assay Promising for Pancreatic Cancer DetectionFRIDAY, Feb. 28, 2025 (HealthDay News) -- A rapid nanosensor assay that measures serum protease cleavage of a target-probe nanosensor can identify pancreatic ductal adenocarcinoma (PDAC ...
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