COVID-19 accelerates the progression of atherosclerotic plaques, increasing coronary inflammation and the risk of high-risk ...

Detection of vulnerable or rupture-prone lesions is of paramount ... In order to detect a vulnerable atherosclerotic plaque that is more likely to cause cardiovascular events, one should focus ...

During the progression of atherosclerosis, development of plaques is initiated by the arterial accumulation and oxidation of low-density lipoproteins (LDLs). This initiates an inflammatory process ...

Acute coronary events frequently result from atherosclerotic plaque rupture at apparently noncritical sites. Although pathologic examination shows that specific plaque characteristics correlate ...

Atherosclerotic plaques form over decades through the deposition of blood lipids such as cholesterol in the innermost layer of the vessel wall. As the plaques become unstable and rupture ...

These lesions, called atherosclerotic plaques, result in the hardening and obstruction of the arteries; moreover, rupture of ...

Tissue factor, a key protein component of the clotting cascade, is located, among many other places, within the necrotic core of atherosclerotic plaques. With “plaque rupture” or “plaque ...

[14] However, they are unable to provide information on cell biologic evens that determine risk of plaque rupture. Different constituents of atherosclerosis, including radiolabeled lipoproteins ...

with a correspondingly thin fibrous cap — a vulnerable plaque prone to rupture and thrombosis. Atherosclerotic plaques typically progress to the advancing atheroma stage at age 55 years to 65 years.

A research team revealed that insulin-like growth factor-binding protein 6 (IGFBP6) serves as a potential therapeutic target ...