Human IgG is a complex molecule composed of four protein chains with attached carbohydrates. A full-size IgG antibody is a Y ... to a Fab of Avastin (bevacizumab; Genentech), which is a full ...

The antibody molecule in particular has been the focus of extensive development of different combinatorial strategies in order to obtain antibodies with novel specificities. These strategies ...

The flurry of deals comes as Roche is facing biosimilar competition for its ‘big three’ antibodies – Rituxan, Herceptin and Avastin ... particularly in small-molecule R&D.