Axons connect neurons across great distances in the nervous system, and this distance is a fundamental vulnerability for neurons. Maintenance of functional connectivity requires robust mechanisms for ...

My lab studies how neuronal circuits form during embryonic development. Specifically, we identify and study genes required for the correct navigation of neuronal processes (axons and dendrites), a ...

The latest map in Science contains never-before-seen details of brain structure, including a rare but powerful set of axons ...

The case in the CNS is illustrated. Following demyelination, a demyelinated axon has two possible fates. The normal response to demyelination, at least in most experimental models, is spontaneous ...