They also show that models learned from nonsynonymous mutations and from out-of-frame sequences are different, prompting new questions about germinal center function. Strengths of the study include an ...

B. (2012)TNF-mediated macrophage activation in the target organ is critical for clinical manifestation of ... (2010) TNFR1 signalling is a critical checkpoint for developing macrophages that control T ...

Iron-dependent ferroptosis, a non-apoptotic cell death mechanism, is gaining attention for its role in immune suppression.

Host cells activate cell death pathways in response to bacterial manipulation of innate immune signalling, but the molecular ...

The platform’s first candidate, INB-619, targets CD19, a key marker broadly found on B cells, which play a central role in leukemias, lymphomas, and autoimmune diseases. In preclinical models, INB-619 ...