Recognition of specific antigen through the B-cell receptor (BCR) stimulates the activation of B cells, which ultimately results in the production of high-affinity antibodies and the provision of ...

A common theme for all of the projects listed above is the analysis of intracellular signaling processes that promote B cell activation, survival and differentiation. The laboratory has a ...

We demonstrate here that cell surface expression of HSPG alone is insufficient for AAV infection, and that AAV also requires human fibroblast growth factor receptor 1 (FGFR1) as a co-receptor for ...