Rituximab, a CD20-specific monoclonal antibody that depletes B cells, has shown promising results in patients with relapsing-remitting multiple sclerosis. Studies of experimental autoimmune ...

It is likely that B-cell-derived regulatory IL-10 has evolved to serve distinct immune functions, and that these functions are in turn carefully regulated in a cell-subset- and context-dependent ...

Induces potent and long-lasting immune responses to defined antigens or whole pathogens (particles), mainly through the ...

Scientists mapped how the human immune system evolves from birth to old age, revealing key changes that influence health, ...

Antibody-producing B cells begin to malfunction early after infection with HIV, for reasons that are poorly understood. In August 14 on-line Proceedings of the National Academy of Sciences Susan Moir ...

Talimogene laherparepvec (T-VEC) demonstrates efficacy in cutaneous BCC, enhancing resectability and altering immune cell ...

Glyco-immunology provides a new approach to treating autoimmunity by enhancing depletion of activated memory B cells, the pathogenic subset of B cells associated with disease progression and often ...