The decrease in CD4 cells during HIV infection seems to be driven by immune activation, which does not always correlate with viral load. Experienced clinicians are all too familiar with the ...

It’s important for all people with HIV to have regular blood tests. The two most important blood tests are for CD4 and viral load. CD4 and viral load test results give essential information about the ...

For HIV to develop into full-blown AIDS, the virus must deplete a subset of immune cells called CD4+ T cells, disabling an infected person’s adaptive immune system in the process. The details of ...

Two research teams led by Warner Greene at the Gladstone Institutes in San Francisco have demonstrated that the vast majority of CD4 T cells in lymphoid tissues, despite their ability to resist full ...

CD4-positive T cells are a subtype of lymphocyte. They are MHC class II-restricted and are important mediators of adaptive immunity. These cells are involved in both the induction and the ...