为解决 IBD 患者 VTE 发病机制不明的问题,爱尔兰皇家外科医学院的研究人员开展组织因子相关研究。结果发现 CD4+TF+ T 细胞及活化 PC 的调节作用。这为理解 IBD 与 VTE 关系及开发新疗法提供依据,强烈推荐科研读者阅读。
我还清楚地记得2018年CAR-T细胞治疗领域发生的两件大事儿。 近日,由纪念斯隆-凯特琳癌症中心Sham ...
CD4 interacts with both the engaged TCR and with invariant sites on the engaged MHC molecules 5,6,7.Inside the cell, the cytoplasmic tail of CD4 binds the src-tyrosine kinase Lck (ref. 8), a ...
S3). Immunohistochemical analysis showed a dense lymphocytic infiltration of the lamina propria positive for T-cell receptor (TCR) α, CD3, CD4, and granzyme B but which did not express TRBC1 ...