为探究 STING 对 CD8? T 细胞代谢的影响,东南大学等单位研究人员开展相关研究。结果发现 STING 通过 HK2 / 乳酸 / IFN-γ 轴影响 CD8? T 细胞功能和记忆分化。该研究为 STING 低表达患者提供新治疗策略,值得科研读者一读。 在肿瘤治疗的战场上,能量代谢的研究正 ...
CD8-positive T cells are a critical subpopulation of MHC class I-restricted T cell and are mediators of adaptive immunity. They include cytotoxic T cells, which are important for killing cancerous ...