For patients with relapsed/refractory chronic lymphocytic leukemia, extended treatment with Imbruvica and Venclexta was found ...
Investigators found that lipid metabolism disruptions spark T-cell dysfunction in patients with chronic lymphocytic leukemia.
Tumor lysis syndrome: rapid tumor breakdown causing harmful substances in the blood. Basal cell and squamous cell carcinomas: common skin cancers affecting different skin cells. Chemoimmunotherapy: ...
"Patients with treatment-naive CLL have several treatment options ... pointed to the fact that there were no cases of substantial clinical tumor lysis syndrome (TLS) in AMPLIFY; the risk of ...
Genetic abnormalities, including deletions (5q-, 7q-, 20q-) and mutations in splicing genes (SF3B1, SRSF2), epigenetic regulators (ASXL1, TET2), and tumor suppressors (TP53), guide prognosis and ...
ICP-248 exerts anti-tumor activity by selectively inhibiting ... will provide deeper remission for treatment-naïve CLL/SLL patients without drug-resistant mutations, bringing hope of clinical ...