点击蓝字关注我们【导读】汇集光学筛选可以研究大规模的细胞相互作用、形态学或动力学，但它们尚未利用高度复杂的单细胞分辨转录组读数的力量为分子通路提供信息。2025年3月12日，美国麻省理工学院/哈佛大学的研究团队在期刊《Cell》上发表了题为“Simu ...

Because the screen can be carried out before preclinical and clinical development begins, it has potential to cut development costs and drive early go/no‑go decisions. How do your CRISPR ...

Schmid Burgk and first author of the paper. "For a conventional CRISPR screen, it often takes months to precisely separate the cells according to their function." Another advantage of the new ...

CRISPR libraries enable scientists to systematically investigate gene functions, identify novel drug targets, and develop personalized therapies.

Suffering on such an immense scale can appear hopeless. However, a technique called CRISPR gene editing promises to help deal with these issues and many more—and wise regulation can spur it on.

CRISPR is a technology that can be used to edit genes and, as such, will likely change the world. The essence of CRISPR is simple: it’s a way of finding a specific bit of DNA inside a cell.

Get Instant Summarized Text (Gist) An enhanced CRISPR tool, CRISPR-Cas12a, has been developed to enable simultaneous assessment of multiple genetic changes, improving disease modeling and gene editing ...

A high throughput screen of >30,000 diverse repressor domains ... (Scribe), a genetic medicines company unlocking the potential of CRISPR to transform human health, presented data on its ...

Technologies like CRISPR are making it possible to quickly ... Today, genes can be edited almost as easily as words on a computer screen. This new ability to alter our DNA holds the promise ...