“The approach, at first glance, seems simplistic and naive,” cancer researcher Robert Weinberg of MIT’s Whitehead Institute for Biomedical Research writes in an email to The Scientist. “Why should an ...

Arcus Biosciences Inc. has disclosed mast/stem cell growth factor receptor Kit (KIT; c-Kit; CD117) inhibitors reported to be useful for the treatment of cancer, allergy, autoimmune, inflammatory, ...

Having proven cell permeability and activity in cancer cells, as well as target selectivity, the researchers now need to show the inhibitors work in preclinical cancer models. More information ...

A team of scientists from The University of Texas Health Science Center at San Antonio (UT Health San Antonio) has identified a promising new drug target for acute myeloid leukemia (AML), a deadly ...

A graphic showing, top to bottom, how DNA aptamers target two specific markers on a leukemia stem cell’s surface, enter the cell and deliver anticancer drugs, resulting in death of the cancer cell.

Northwestern Medicine scientists have uncovered new details about the genetic structure of ovarian cancer stem cells, ...

There’s an opportunity of using stem cells to control ovarian cancer ... they don’t have some of the natural inhibitors that an adult NK cell has, so they just kill dramatically quickly ...

Studies have demonstrated that stem cells have potential applications in treating a range of diseases, including cancer and heart disease. Cytokines play a pivotal role in stem cell renewal and ...

A novel cell therapy approach using cord blood-derived natural killer (NK) cells pre-complexed with AFM13, or acimtamig, a CD30/CD16A bispecific antibody, was safe and generated strong response rates ...

Drug-carrying DNA aptamers can deliver a one-two punch to leukemia by precisely targeting the elusive cancer stem cells that seed ... the drug once inside the cell so the drug can act.

WASHINGTON (AP) — A man who battled childhood cancer has received the first known transplant of sperm-producing stem cells, in a study aimed at restoring the fertility of cancer’s youngest ...