Sustained exposure to pathological stress stimulates the heart to hypertrophy, increasing disease and mortality risk. New therapies to blunt this process include targeting enzymes below the cell ...

High-intensity exercise raises sudden cardiac death risk in young hypertrophic cardiomyopathy patients, independent of ...

Aim Differentiating physiological cardiac hypertrophy from pathology is challenging when the athlete presents with extreme anthropometry. While upper normal limits exist for maximal left ventricular ...

多项报道和研究者前期的工作已经证实，心肌肥厚时，亚硝基谷胱甘肽还原酶（S-nitrosoglutathione reductase, GSNOR）表达降低，导致多种蛋白质SNO修饰水平升高，促进心肌肥厚和心衰。但是GSNOR在心肌肥厚中下调的具体原因及干预手段仍不清楚。

Another active area of research in the laboratory focuses on unraveling the mechanisms behind maladaptive, or pathological, and adaptive, or physiological, cardiac hypertrophy. In response to certain ...

The following is a summary of “Role of glucocorticoid receptor expression in Chronic Chagas Cardiomyopathy: implications for ...

Obesity significantly impacts cardiovascular health, increasing risks such as left ventricular hypertrophy, atherosclerosis, ...

Right ventricular hypertrophy occurs when the right ventricular wall thickens due to chronic pressure overload, similar to that of left ventricular hypertrophy. RVH is diagnosed on ECG in the ...

The study links exertional heat stroke to chronic disorders, revealing impacts on body mass regulation and heart health, ...

Aldosterone has been shown to cause coronary inflammation, cardiac hypertrophy, myocardial fibrosis, ventricular arrhythmias, and ischemic and necrotic lesions. There are currently two aldosterone ...

A recent study validated new thresholds for left ventricular hypertrophy to improve both HCM diagnosis and timely treatment of HCM.