近日，上海交通大学生命科学技术学院谢志平研究员团队在Cell Death & Differentiation杂志上在线发表了题为Temporal dissection of the roles of Atg4 and ESCRT in autophagosome formation in yeast的研究论文。本研究发现Atg4催化自噬体膜上Atg8的解离构成自噬体膜闭合的新通路，与ESCRT的晚 ...

为解决 YAP 活性调控及相关疾病治疗难题，复旦大学等单位研究人员开展 LINC01315 编码蛋白 YAPer-ORF 研究，发现其可调控 YAP 信号促细胞生长。该成果为相关疾病治疗提供新靶点，值得科研人员一读。 在生命科学的研究领域中，Hippo-YAP 信号通路（是一种在进化上 ...

为探究脉络膜黑色素瘤（UM）中血管生成拟态（VM）形成机制及治疗策略，研究人员开展研究，发现关键因素并提出联合治疗方案，为 UM 治疗提供新思路。 脉络膜黑色素瘤研究新突破：揭示 VM 形成机制与联合治疗方案 在人体的眼睛中，脉络膜黑色素瘤（Uveal ...

As cells are infected by microorganisms, they can pre-emptively die to prevent the replication and spreading of the pathogen. Cell death that is associated with the presence of pathogen-associated ...

Shihabeddin et al utilized single-cell RNA-Seq analysis of adult P23H zebrafish animals to identify transcription factors (e2fs, Prdm1a, Sp1) expressed selectively in neural progenitors and immature ...

Using an unbiased approach, this important study discovered a role of Ezh2 in the differentiation of granule neuron precursors, the cell of origin for Shh group of medulloblastoma. Furthermore, the ...

Cells with electrophysiological activity obtained at the University of the Basque Country (UPV/EHU) are opening up new ...

The research team investigated the regulatory mechanisms that guide the optimal differentiation of T cells into specific lineages while inhibiting others. To do this, they used a technique called ...

The sugar glucose, which is the main source of energy in almost every living cell, has been revealed in a Stanford Medicine study to also be a master regulator of tissue differentiation - the process ...

An initial autopsy on the body of Pol Col Thitisan "Joe Ferrari" Utthanaphon has indicated the probable cause of death was suicide by hanging, according to the Central Institute of Forensic ...

Ontario’s police watchdog agency is investigating the death of an individual who had gone into medical distress while in a cell at the Ottawa courthouse on Monday. In a release on Tuesday, March ...