In a significant discovery, the study identified a 150-gene starter cell signature that was associated with poor clinical outcomes across multiple datasets. The signature's predictive power for ...

the single cell molecular sequencing found a gene signature on these BMP-like cells that predicted poor outcome across multiple subtypes of T-ALL. By knowing its gene signature, researchers then ...

Molecularly defined serotonin (enterochromaffin) cells of the gut lining were distinguished by single-cell expression analysis, in situ hybridization, and immunohistochemistry into 14 topographically ...

This paper explores the potential of mitochondrial-associated programmed-cell-death (mtPCD) patterns as biomarkers for predicting the prognosis of non-small-cell lung cancer (NSCLC). NSCLC is the most ...

Colorectal cancer (CRC), a type of cancer that affects the large intestine and rectum, is one of the leading causes of cancer-related deaths worldwide. The mutational landscape of CRC is ...

How cardiac cell fates are specified during heart development remains elusive. This study identifies a level-dependent role for transcription factor HAND1 in mesoderm patterning and the specification ...

A gene known as HbS was the center of a medical and evolutionary detective story that began in the middle 1940s in Africa. Doctors noticed that patients who had sickle cell anemia, a serious ...

Drexel's Master of Science in Biomedicine and Cell and Gene Therapy program offers a unique graduate-level opportunity for students at the intersection of medicine and bioengineering. An ever-evolving ...

Each gene might have different forms, and these are called alleles. The diagram shows the relationship between the cell, its nucleus, chromosomes in the nucleus, and genes.

Cell and gene therapy involves extracting cells, protein or genetic material from a patient or donor and altering them to provide a highly personalised therapy. These therapies have shown potential to ...