Next the scientists generated transgenic mice from bacterial artificial chromosomes in which this protein was under the control of a cell type–specific promoter. GFP-tagged ribosomes would then ...

A robust platform for analyzing 3D genome architecture and epigenomic features enables a deeper understanding of gene regulation in specific cell types. Researchers analyze various aspects of gene ...

Promoters, which initiate gene transcription, exhibited a dependence on sequence orientation but were less cell-type specific. Enhancers, which amplify gene transcription, showed cell-type ...

[172] Considering these possible modifications (cell type-specific promoter-driven expression of the transgene in combination with a suicide gene, insulator and S/MAR, and pseudotyping with an env ...

Promoters, which start gene transcription, showed a dependence on sequence orientation but were less specific to cell types. Enhancers, which boost gene transcription, were active regardless of ...