A robust platform for analyzing 3D genome architecture and epigenomic features enables a deeper understanding of gene regulation in specific cell types. Researchers analyze various aspects of gene ...

[172] Considering these possible modifications (cell type-specific promoter-driven expression of the transgene in combination with a suicide gene, insulator and S/MAR, and pseudotyping with an env ...

Promoters, which initiate gene transcription, exhibited a dependence on sequence orientation but were less cell-type specific. Enhancers, which amplify gene transcription, showed cell-type ...

Activator proteins bind to regulatory sites on DNA nearby to promoter ... specific combinations of regulators on and off. Such developmental patterns are responsible for the variety of cell types ...

Neuropsychiatric disorders are becoming increasingly prevalent. Given their complex and multifactorial pathogenesis, there is ...

Promoters, which start gene transcription, showed a dependence on sequence orientation but were less specific to cell types. Enhancers, which boost gene transcription, were active regardless of ...