The maintenance of DNA methylation and histone modifications is interconnected at the replication fork. The centromere-specific histone H3 variant CenH3 (CENP-A in humans) is inherited in a ...

The fusion protein binds to the LacO domains (1), and incorporates the specialized centromeric histone CENP-A into and along neighboring chromatin (2). In turn, the region of CENP-A-containing ...

They analyzed how centromere-specific histone 3 (CENH3) influences the targeting and insertion of these elements, and explored the role of retrotransposons in centromere dynamics. Centromeres ...

Michael Lampson, PhD is a cell biologist at the University of Pennsylvania. His research group focuses on cell division, centromere function in the germline, and the cell biology of meiotic drive.