The fusion protein binds to the LacO domains (1), and incorporates the specialized centromeric histone CENP-A into and along neighboring chromatin (2). In turn, the region of CENP-A-containing ...
来自MSN10 个月
Researchers reveal how acetylation regulates centromere dynamics, chromosome segregation ...The centromere, a specialized region of the chromosome ... Subsequent studies revealed that not only histones but also numerous non-histone proteins are subject to acetylation modifications ...
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