These mice were conditioned with chemotherapy and then treated using ... Moreover, such robust control of late-stage solid tumors has not yet been accomplished in previous studies, even with ...

CAR-T cell therapies trigger deep responses in hematological malignancies but investigations in solid tumors ... the use of toxic immune-depleting chemotherapy. Rapa has begun to validate its ...

The FDA cleared the investigational new drug application for ALX2004, with phase 1 trials expected to begin in mid-2025 for ...

The GI Cancers Symposium revealed new therapies for specific cancer subsets and progress in chimeric antigen receptor T-cell ...

This approach not only elicited responses on its own against solid tumors and metastatic disease but also enhanced the efficacy of multiple therapies. That includes different chemotherapy ...

The side effects of chemotherapy depend on the type of drug involved. Common side effects include infections, easy bruising or bleeding, and hair loss. Chemotherapy kills regular cells ...

The particles can be targeted directly to tumors, where they release their payload while avoiding many of the side effects of traditional chemotherapy. Polymer-coated nanoparticles loaded with ...

Five nurses who worked on the same floor of a Boston-area hospital have all developed brain tumors. In total ... nearby X-rays and chemotherapy treatment on the floor below as potential triggers ...

Our pipeline includes two Phase 1 therapies in development for solid tumors: ALTA2618, a first-in-class, oral mutation-selective inhibitor for AKT1 E17K-driven cancers, and ALTA3263, a potential ...

The committee based its decision on data showing the subcutaneous formulation of Opdivo was not inferior to the intravenous formulation.

- Trials are designed to demonstrate whether the addition of Actimab-A to either KEYTRUDA ® or OPDIVO ® can result in improved patient outcomes - MDSCs – Myeloid Derived Suppressor Cells in ...

The chemotherapy passes from the liver into the bile ducts. HAI therapy may be used to shrink tumors before surgery. Targeted Therapies for Bile Duct Cancer Targeted therapies block specific changes ...