You can expect three times the transcriptional yield (4 mg/mL) and a much-improved capping efficiency (>95%) over traditional methods. The mRNA cap structure is an important point of consideration for ...

With this agreement with Aldevron, TriLink strengthens its objective to provide greater access to CleanCap® mRNA capping technologies to those developing critical mRNA-based therapeutics and ...

According to the terms of the agreement, TriLink will supply its patented CleanCap M6, CleanCap AG 3’OMe, CleanCap AG, and CleanCap AU cap analogs for use in Aldevron’s mRNA development and ...

Abe's team overcame this hurdle by introducing a cap structure into the circular mRNA itself. This internal cap structure triggers translation initiation, bypassing the need for IRES sequences ...