Mass General Brigham researchers discovered a previously unknown mechanism that may drive tissue damage and a new target for drug discovery ...

The complement pathway is a part of the immune system. You have about 50 proteins in this system. Viruses, bacteria, or an injury can trigger one protein to activate another. This complement ...

Our immune system is armed with an array of defenses designed to detect and eliminate harmful threats. One of its most powerful defense mechanisms is the complement system-a group of proteins that ...

The eye-care company Alcon Research has entered into licensing and purchase option agreements with Potentia Pharmaceuticals to develop Potentia's leading drug candidate — a complement pathway ...

The complement proteins C3 and protease factor B have a central role in the activation pathways of the complement system. Recent advances in the structural biology of complement protein C3 ...

Preclinical studies have shown their potential to reduce inflammation and modulate immune responses in diseases like rheumatoid arthritis and lupus.

Omeros Corporation (Nasdaq: OMER) today announced two presentations that will be featured at the 2025 Tandem Meetings – the ...

Importantly, inhibition of MASP-2 has been demonstrated to leave intact the antibody-dependent classical complement activation pathway, which is a critical component of the acquired immune ...

Researchers discovered a previously unknown mechanism that may drive tissue damage and a new target for drug discovery.