The “classical” pathway of the complement system is triggered when C1q binds to antibodies that are already bound to antigens on a cell surface. It only comes into effect when a high number of ...

reveal an unexpected role for complement proteins ... parallels between the molecular contributors to immune- and nervous-system function. Future work will unpick the links between synaptic ...

Modulation of the complement system — a key component of innate ... effector functions independently of the activation pathway; this could be important in targeting AMD at an early stage.