The “classical” pathway of the complement system is triggered when C1q binds to antibodies that are already bound to antigens on a cell surface. It only comes into effect when a high number of ...

Mannan-binding lectin (MBL), M-, L- and H-ficolin recognize microorganisms and activate the complement system via MBL-associated serine proteases (MASPs). We investigated lectin pathway cord blood ...

Modulation of the complement system — a key component of innate ... effector functions independently of the activation pathway; this could be important in targeting AMD at an early stage.