Researchers use cortical organoids to answer fundamental questions such as how the human brain can grow to its large size or ...

The paper, by A. Amiri at Yale University in New Haven, CT, and colleagues was titled, "Transcriptome and epigenome landscape of human cortical development modeled in organoids." Advanced Search Home ...

Using human brain organoids as a model for brain development and disease research has been a game changer, providing Arlotta a novel view into brain pathologies that form in utero. Why are ...

Organoids, or self-organizing miniature organs, represent a powerful new tool to study organogenesis or model diseases and are considered a means to generate cells and tissues for cell ...

Using a large-scale library of TC organoids they developed, the researchers performed comprehensive comparative analyses of chemo-sensitive and chemo-resistant cells. Their efforts shed light on ...

Using patient-derived brain organoids, they showed that activating the mTOR pathway prevents and reverses thickened cortical structures. This points to a potential universal treatment for the ...