One-step creation of Cre-loxP organisms: Precise control and modification of gene expression
Researchers at the University of Tsukuba have developed a vector that integrates the Cre enzyme gene with the specific DNA ...
生物通13 天
TAx9 技术：突破 Cre-loxP 系统构建难题，加速基因编辑研究进程
研究人员为解决 Cre-loxP 单质粒合成难题，开展 TAx9 相关研究，成功创建 F0 代转基因动物，意义重大。 开启基因编辑新征程：TAx9 技术的诞生 在生命科学的奇妙世界里，基因编辑技术宛如一把神奇的 “剪刀”，帮助科学家们探索生命的奥秘。其中，Cre-loxP 系统 ...
The Scientist1 年
Infographic: The Cre-lox System Explained
The resulting experimental mouse is hemizygous for Cre and homozygous for loxP (D). This is the necessary genotype required to conditionally knock out the target gene in the specific tissue. Laura is ...
EurekAlert!2 年
c-kit IRES-Cre Mice Allow for Molecular Layer Interneurons Targeting in Mature Mice (IMAGE)
The cerebella from c-kit IRES-Cre mice injected with Cre-reporter virus at PND (pups shortly after birth) 0 or PND 64. Tissue was prepared from animals 27 and 14 days after injection ...