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生物通
1 个月
解析 DNA 损伤奥秘:单细胞测序揭示损伤与基因调控关联及疾病风险
为解决分析 DNA 损伤受细胞组成和损伤随机性干扰的问题,研究人员开发 Paired-Damage-seq,发现损伤与表观遗传变化有关,可预测疾病风险。 在多细胞生物中,基因组完整性的维持对分子程序至关重要。在整个生命过程中,各种内源性和环境因素持续威胁基因组 ...
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