Causes: LIG4 syndrome is caused by a mutation in the LIG4 gene, which carries the instructions needed to make a protein known as DNA ligase 4. This protein is an enzyme that helps repair a ...

In contrast, yeast DNA ligase IV is not essential for cell growth. However, deletion of the LIG4 gene elicits phenotypes indicating that ligase IV catalyzes the repair of double-strand breaks in the ...

But James Watson and Francis Crick's claim was a valid one, for they had in fact discovered the structure of DNA, the chemical that encodes instructions for building and replicating almost all ...