A team of staff from the Faculty of Biology of Moscow State University and the Belozersky Research Institute of Physico-Chemical Biology of Moscow State University has proposed a convenient method for ...

Homologous recombination plays essential roles in the repair of DNA double strand breaks (DSBs) and collapsed replication forks. The fundamental reaction in homologous recombination is the exchange of ...

Poly(ADP-ribose) polymerase (PARP) inhibitors (PARPis) are promising cancer treatments because they block a cell’s ability to repair DNA damage. Four PARPis are currently approved for use in the ...

Researchers at the University of Toronto have discovered a DNA repair mechanism that advances understanding of how human ...

Mutations in BRCA2—a gene known to repair damaged DNA and suppress tumor formation—can predict an individual's predisposition ...

DNA repair proteins act like the body's editors, constantly finding and reversing damage to our genetic code. Researchers ...

Mutations in BRCA1 and BRCA2 -- tumor suppressor genes that play a crucial role in DNA repair -- substantially increase the likelihood of cancer.

The Pol-theta enzyme (blue) joins two parts of a broken DNA strand (yellow). This process is mutagenic and can give rise to cancer. LA JOLLA, CA—DNA repair proteins act like the body’s editors ...

DNA repair proteins act like the body's editors, constantly finding and reversing damage to our genetic code. Researchers have long struggled to understand how cancer cells hijack one of these ...