so histones bind with DNA very tightly. The basic repeating structural (and functional) unit of chromatin is the nucleosome, which contains eight histone proteins and about 146 base pairs of DNA ...

Northwestern Medicine scientists have uncovered new details about the genetic structure of ovarian cancer stem cells, ...

Other researchers sequencing the Greenland shark’s genome recently found another hint to their superpower: multiple copies of 81 genes involved in DNA repair. In particular, they found that the ...

Research shows UV radiation modifies 3D genome structure, affecting DNA damage response and gene activity, offering insights ...

Live confocal microscopy of DNA repair in oocytes from young and aged mice expressing 53BP1-mClover (green) together with 5’-SiR-Hoechst (chromatin, magenta). Oocytes were treated with NCS and ...

Ring-shaped extrachromosomal DNA is implicated in many cancers. Rachel Brazil talks to the scientists trying to uncover their ...

This process is mutagenic and can give rise to cancer. LA JOLLA, CA—DNA repair proteins act like the body’s editors, constantly finding and reversing damage to our genetic code. Researchers ...

Now, for the first time, EMBL scientists have directly observed this process in high resolution under the microscope using a new chromatin tracing method. The new study shows that the long DNA ...

DNA repair proteins act like the body's editors, constantly finding and reversing damage to our genetic code. Researchers have long struggled to understand how cancer cells hijack one of these ...