During DNA replication, the unwinding of strands leaves a single strand vulnerable ... always requires CMG function to create the ssDNA template, it could never surpass the DNA helicase (Figure ...

Original DNA template - DNA is a double helix made of two complementary strands. Each strand can be used as a template to create a new DNA molecule. Free DNA nucleotides – needed to form the new ...

Trends in Genetics 22, 46–55 (2006). Argueso, J. L. et al. Double-strand breaks associated with repetitive DNA can reshape the genome. Proceedings of the Naitonal Academy of Sciences 105 ...

The DNA repair and replication pathways converge on a common final step in which the continuity ... The NTase domain binds to the broken DNA strands at and flanking the nick, the OB domain contacts ...

DNA replication is the process by which the DNA molecule makes an exact copy of itself during cell division. The double helix unwinds, and each strand serves as a template for the synthesis of a new ...

During DNA replication, special enzymes move up along the DNA ladder, unzipping the molecule as it moves along. New nucleotides move in to each side of the unzipped ladder. The bases on these ...

During DNA replication, the complementary base pairing of thymine with adenine ensures the accurate copying of genetic information. DNA polymerase enzymes use the existing DNA strand as a template and ...

While scientists have long known the importance of helicase in DNA replication ... must first unwind and break the DNA from a double strand into two single strands. Credit: Taha Shahid et ...

To maintain its orderly structure, single rings on one strand can only bond with ... by providing raw nucleobases and a template DNA sample to DNA replication enzymes from bacteria.

DNA achieves this feat of storing, coding and transferring biological information though its unique structure. Replication of DNA DNA replication is the process by which a cell makes an identical ...

When organisms encounter problems—what scientists call "replication stress"—this ... And one of the things it can get stuck ...