Next-generation DNA sequencing has started a revolution in ... One of the tricks to getting tSMS to work is in the next step in the process: the labeling dye is cleaved off, allowing incorporation ...

This image compares three DNA sequencing technologies: Sanger sequencing, Massively Parallel DNA sequencing, and Nanopore DNA sequencing. Sanger sequencing (left) sequences 500-700 bases per reaction ...

Researchers at the University of Toronto have invented a new method that uses DNA sequencing to measure metabolites. This ...

Long-read, single-molecule DNA sequencing is a foundational method in genomics research, with applications including identifying complex structural variants and analyzing whole chromosomes. However, ...

Ancient DNA studies provide critical insights into human evolution and extinct species, leveraging advanced techniques to ...

DNA methylation is a fundamental epigenetic mechanism in which a methyl group ... Targeted bisulfite sequencing relies on two PCR amplification steps after bisulfite conversion, followed by deep ...

In the case of cancer analyses, the sequencing step ultimately detects circulating tumor-derived DNA fragments (ctDNA) from the tumor of origin within the total collection of cfDNA. To improve the ...

Biology has yet to tap into the full benefits of computer simulations, but a new AI foundation model developed by a team of scientists including CMU's Eric Xing hopes to change that.