Nature1 个月
DNA double-strand breaks: signaling, repair and the cancer connection
Of the many types of DNA damage that exist within the cell, probably the most dangerous is the DSB. These result from ... forks encounter DNA single-strand breaks or other types of lesion.
Nature4 年
Repairing Double-Strand DNA Breaks
To study DSB repair using this system ... et al. Regulation of DNA double-strand break repair pathway choice. Cell Research 18, 134–147 (2008). Singh, R. K. & Krishna, M. DNA strand breaks ...
来自MSN1 个月
In vitro reconstitution of meiotic DNA double-strand breaks: A long-standing challenge solved
However, despite nearly three decades of efforts, reconstituting DSB formation in vitro has ... In vitro reconstitution of meiotic DNA double-strand-break formation, Nature (2025).