We propose that targeting the metabolic defects in this pathway might provide an opportunity for the development of kidney cancer gene-specific therapies that are more durable and more effective ...

could lead to the development ... Scientists have examined the gene expression patterns of single cells from 5 human fetal kidneys to create the most complete atlas of the fetal kidney to date.

The kidney is a major site of organ damage caused by drug toxicity. This frequently manifests during drug development and/or in standard clinical care. Nephrotoxicity resulting from drug exposure ...

The team indicates that different genetic predispositions give rise to different tumor development pathways and kidney structures, and have identified those that restrict the growth of tumors.

New research looked at how cancers arise in children who are predisposed to developing the childhood kidney cancer, Wilms tumor, which could help anticipate the development of tumors before they ...

Kuure lab studies mechanisms of organogenesis with the focus on embryonic kidney and in vivo modeling of rare diseases. Congenital renal malformations are among the most common birth defects and arise ...

“We believe this work can form a foundation for the development of neoantigen vaccines in kidney cancer,” said Braun.

Kidney stone development involves various factors, including genetic predisposition and environmental influences, specifically dietary habits. Addressing these modifiable risk factors is crucial ...