ibuprofen and diclofenac). The primary outcome measure was myocardial infarction (fatal or nonfatal). Secondary outcome measures were stroke (fatal or nonfatal), cardiovascular death (death ...

The mechanism of action of diclofenac, like that of other NSAIDs, is not completely understood but involves inhibition of cyclooxygenase (COX-1 and COX-2). Increased risk of serious cardiovascular ...

Diclofenac sodium 3% ... Nursing mothers. Avoid concomitant aspirin, salicylates (eg, diflunisal, salsalate) or other NSAIDs. Increased risk of GI bleed with anticoagulants, antiplatelets ...

Diclofenac potassium is a phenylacetic acid NSAID with a faster onset of PAR than the standard formulation, diclofenac sodium. [17] It is used in many countries for treatment of acute pain ...

The most commonly used NSAID among the 157,025 non-aspirin NSAID users was diclofenac (42.9%), primarily in the first and second trimesters, followed by mefenamic acid (35.6%) and ibuprofen (20.4%).