A double-strand DNA break (DSB) occurs or arises when both strands of the DNA duplex are severed, often as the result of ionizing radiation. They are particularly deleterious as the DNA ends can ...

Trends in Genetics 22, 46–55 (2006). Argueso, J. L. et al. Double-strand breaks associated with repetitive DNA can reshape the genome. Proceedings of the Naitonal Academy of Sciences 105 ...

To maintain its orderly structure, single rings on one strand can only bond with double ... Sanger sequencing uses electrophoresis to draw DNA molecules through a gel filter, producing ...

Sanger sequencing uses electrophoresis to draw DNA molecules through a gel filter ... To maintain its orderly structure, ...

In a study published in Nature, researchers report the successful in vitro reconstitution of meiotic DNA double-strand breaks (DSBs) formation. Meiosis, a specialized form of cell division in most ...