We hypothesized that the syntrophins function as molecular anchors to link dystrophin and utrophin to other cell structures. To understand the organization of the utrophin complex at neuromuscular ...

The life expectancy of affected patients is significantly reduced. The disease, for which there is currently no cure, is caused by mutations in the dystrophin gene, which is located on the X ...

A new study has shed light on the complex interactions between dystrophin, a protein critical to muscle stability, and its partner protein, dystrobrevin, offering new pathways for understanding ...

Dystrophin is an integral component of the dystrophin-glycoprotein complex (DGC), a large protein assembly that links the intracellular cytoskeleton of muscle fibers to the extracellular matrix.

Dystrophin is part of a protein complex linking the cytoskeleton of muscle fibers to the surrounding connective tissue (basal lamina). It’s a long protein with numerous redundant coils (purple balls), ...