The life expectancy of affected patients is significantly reduced. The disease, for which there is currently no cure, is caused by mutations in the dystrophin gene, which is located on the X ...

DMD is an X-linked disorder characterized by progressive muscle weakness and wasting due to the absence of a protein called dystrophin, which in turn causes degeneration of skeletal and cardiac muscle ...

SAST and syntrophin were highly associated with purified microtubules and microtubule-associated proteins, whereas utrophin and dystrophin were only partially associated with microtubules.