In 2000, it was suggested to me that “Autophagy will be the wave of the future; it will become the new apoptosis.” Few people would have agreed at the time, but this statement turned out to be ...

A process known as ER-phagy ("ER-eating") plays a central role ... They make contact with the autophagy machinery and direct it toward the membrane. The IDRs then condense into more compact ...