MSC-sec 改善老龄小鼠卵母细胞质量 ：在体外成熟实验中，与年轻小鼠卵母细胞相比，老龄小鼠卵母细胞的第一极体（PB1）排出率较低。添加人脐带间充质干细胞分泌组（hUC-MSC-sec）后，PB1 排出率显著增加，而添加成纤维细胞分泌组（Fib-sec）则无明显变化。同时，hUC-MSC-sec 处理减少了老龄小鼠卵母细胞的纺锤体异常和非整倍体率，表明 MSC-sec ...

GTF3C2 promotes HCC cell proliferation via the USP21/MEK2/ERK1/2 pathway. General transcription factor IIIC subunit 2 (GTF3C2) is one of the polymerase III transcription-related factors.

Alcohol binge increases intestinal permeability by activating intestinal epithelial CB1R-ERK1/2 signalling with subsequently reduced differentiation and downregulation of tight junctions (left).